Human beings, each considered as a single actor within society
- Salerno, Joseph T. - American economist of the Austrian school, professor at Pace University
- Say, Jean-Baptiste - 18th-19th century French economist
- Schiff, Irwin A. - American author, tax protester, 1996 Libertarian Party presidential aspirant
- Scholl, Hans - Member of the White Rose resistance group in Nazi Germany
- Scholl, Sophie - Member of the White Rose resistance group in Nazi Germany
- Schoolland, Ken - Professor of Economics and Political Science, author
- Schulman, J. Neil - American science fiction writer, winner of Prometheus Best Novel and Hall of Fame awards
- Schumpeter, Joseph - 20th century Austrian economist
- Sciabarra, Chris Matthew - Politics scholar at New York University, editor of The Journal of Ayn Rand Studies
- Scientists - Researchers of the natural sciences
- Selleck, Tom - Film and TV actor, starred in TV series "Magnum, P.I."
- Sellers, Peter - British comedian and actor, best known as the original Inspector Cloiseau
- Senior, Nassau William - Nineteenth century English economist
- Sennholz, Hans F. - German-American economist of the Austrian School
- Shaffer, Butler - Professor of law at Southwestern University
- Shaw, Sandy - Expert in anti-aging research and brain biochemistry
- Shermer, Michael - Founding publisher of Skeptic magazine, Executive Director of the Skeptics Society
- Sidney, Algernon - 17th century British Member of Parliament
- Simmons, Randy T. - Political science professor, Mayor of Providence, Utah
- Simon, Julian - Professor of Business Administration, author
- Sirico, Robert A., Rev. - Co-founder and President of the Acton Institute for the Study of Religion and Liberty
- Skousen, Mark - Author, investment advisor, professor of Economics
- Slagle, Tim - Political satirist and stand-up comic
- Slampyak, Ted - Comic strip artist, creator of the Jazz Age Chronicles, currently drawing the "Annie" strip
- Smith, Adam - Eighteenth century Scottish economist, author of The Wealth of Nations
- Smith, Fred L., Jr. - President and founder of the Competitive Enterprise Institute
- Smith, George H. - Writer, author of Why Atheism?
- Smith, L. Neil - American science fiction writer, three-time winner of the Prometheus Best Novel Award
- Smith, Vernon L. - 2002 Nobel Prize winner in Economic Sciences
- Snow, Tony - Host of the "Tony Snow Show" on Fox News Radio
- Sobran, Joseph - Nationally syndicated columnist, past Senior Editor for National Review
- Sociologists - Students of society and social institutions
- Software Engineers - Designers, implementers and testers of computer software
- Sommers, Christina Hoff - Former philosophy professor, author of Who Stole Feminism?
- Soos, Troy - American writer, author of the Mickey Rawlings historical baseball mysteries
- Sowell, Thomas - Author, syndicated columnist, fellow at the Hoover Institution
- Spencer, Herbert - 19th century English philosopher
- Spielberg, Steven - American movie director and producer, Oscar winner for Schindler's List and Saving Private Ryan
- Spooner, Lysander - Lawyer, abolitionist, entrepreneur, legal theorist and political radical
- Stanhope, Doug - American stand-up comic, host of "The Man Show"
- Stephan, Doug - Nationally syndicated radio host of the "Doug Stephan's Good Day" show
- Stern, Howard - "The King of All Media"
- Stigler, George - 20th century American economist, winner of the 1982 Nobel Prize in economics
- Stossel, John - Host of "Stossel" show on Fox Business channel and former ABC News correspondent for the "20/20" newsmagazine
- Stromberg, Joseph R. - Historian, research fellow at The Independent Institute
- Sullum, Jacob - Senior editor of Reason, nationally syndicated columnist
- Sumner, William Graham - Nineteenth century professor of political and social science at Yale University
- Suprynowicz, Vin - Assistant Editorial Page Editor at the Las Vegas Review-Journal, syndicated columnist
- Sykes, Charles J. - Author, radio talk show host at WTMJ in Milwaukee, Wisconsin
- Szasz, Thomas - Psychiatry professor and author
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